INACTIVATION OF NITROFURAN DERIVATIVES BY FENTON REAGENT
Abstract
The result of human evolution and the development of industry was the emergence of global environmental problems on the planet. Pharmaceuticals is one of the rapidly developing industries and, as a result, a "major supplier of pollutants" to the environment. The search for methods to solve the problems of purification and inactivation of organic toxic pollutants is an important task of modern chemistry. The purpose of this study was to study the inactivation of drugs of the nitrofuran group by hydrogen peroxide in the presence of iron (II) ions.
The study of oxidative degradation of furacilin and furagin preparations by Fenton reagent was carried out. The effect of different concentrations of the oxidative system on the destruction of drugs was compared, optimal conditions for destructive processes were determined. The characteristics of the oxidative degradation of the two drugs are compared, the justification of the differences based on the chemical structure of the active substances is proposed.
The effectiveness of the Fenton system for the destruction of nitrofuran class drugs has been confirmed. Chemi-cal methods of destruction of organic pollutants are advanced and can be used for wastewater treatment of medical and pharmaceutical enterprises, as well as for local treatment facilities.
The study of oxidative degradation of furacilin and furagin preparations by Fenton reagent was carried out. The effect of different concentrations of the oxidative system on the destruction of drugs was compared, optimal conditions for destructive processes were determined. The characteristics of the oxidative degradation of the two drugs are compared, the justification of the differences based on the chemical structure of the active substances is proposed.
The effectiveness of the Fenton system for the destruction of nitrofuran class drugs has been confirmed. Chemi-cal methods of destruction of organic pollutants are advanced and can be used for wastewater treatment of medical and pharmaceutical enterprises, as well as for local treatment facilities.

English
Русский