The article considers the problem of neutralization of acidic wastewater generated during the regeneration of cation exchange filters at the Novo-Salavatskaya CHPP. The initial wastewater has a pH of 1.3 and a sulfate content of 11.6 g/dm³. The aim of the work is to develop a technological scheme and neutralization modes that allow obtaining two by-products: alabaster and manganese concentrate. The methods used include potentiometric pH determination, complexometric titration for calcium, and turbidimetry for sulfates. The experiment included two stages: precipitation of calcium sulfate with a 10% CaCl₂ solution and subsequent neutralization of the filtrate in a column packed with carbonate manganese ore. It was found that the optimal solution feed rate through the column is 4.57 cm³/min, at which the pH rises to 6.75 and the sulfate content decreases to 2.15 g/dm³. The CaSO₄ precipitate after calcination at 170–180 °C is converted into alabaster with a yield of 4.6 g per 1 dm³ of wastewater. The insoluble residue of the ore is enriched in MnO₂ up to 34–36% and can be used as a manganese concentrate. It is concluded that the proposed two-stage scheme makes it possible to abandon expensive alkaline reagents and obtain two marketable products.