Sea buckthorn is a unique plant, the medicinal properties of which have been known since antiquity. The greatest value in medical practice is the product of processing the fruits of this plant - sea buckthorn oil. Today there is a problem of press cake utilization after receiving oil by cold pressing method. The organic acids contained in the sea buckthorn fruits are water-soluble, therefore, a minimum amount of them is extracted into the resulting oil, and the entire main part remains in the cake. Organic acids are indispensable elements necessary for the normal functioning of the human body, the study of their composition in the cake would later justify its use as a secondary raw material for various industries. Thus, the purpose of our study was to study the chemical composition of organic acids in sea buckthorn cake by high performance liquid chromatography. Based on the data obtained, it can be concluded that the content of organic acids in the cake is quite high. In this connection, the most rational solution would be the implementation of waste-free production of sea buckthorn oil, involving the use of the re-maining raw materials as secondary raw materials for various industries.