English
Русский 38-44 p.
Development of new sensors for detecting substances in different environments is now of great interest. Voltammetry methods, used in this article, allow one to carry out analysis in the field with almost no sample preparation. This study was carried out to investigate possibilities of quantitative glucose determination on copper quazimicroelectrode in aqueous solutions, including human blood. Process of preparation of copper indicator quazimicroelectrode with effective area consisting of ensemble of copper wires is described in this article. Glucose determination technique in aqueous solutions and the results of testing this electrode in quantitative determination of glycose in human blood are reported. The comparison of the results of investigated copper sensor with reference sensor is carried out. Statistically processed results of glucose determination are described. Copper advantages as electrode material are discussed. Designed electrode can find application in medical analysis laboratories and port-able devices for glucose determination in the field.
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11. High-pH ion-exchange separation and electrochemical detection of alditols, carbohydrates and acidic sugars / Prabhu S.V. at al. // Journal of Chromatography A. 1990. V. 503. №1. R. 227 – 235.
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13. Electrochemical characterization of carbohydrate oxidation at copper electrodes / Marioli J. at al. // Electrochem. Acta. 1992. V. 37. №7. R. 1187 – 1197.
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2. Mednyj i serebryanyj ehlektrody dlya potenciometricheskogo i vol'tamperometricheskogo opredeleniya glyukozy i drugih uglevodov / I.F. Abdullin, G.K. Budnikov, YU.N. Bakanina i dr. // ZHurnal analiticheskoj himii. 1998. T. 53. №10. S. 1075.
3. Electrocatalysis and Amperometric Detection Using an Electrode Made of Copper Oxide and Carbon Paste / Xie Y. at al. // Anal. Chem. 1991. V. 63. №17. R. 1714 – 1719.
4. Luo M.Z. Characterization of carbohydrate oxidation at copper electrodeswin / Luo M.Z. at al. // J. Electroanal. Chem. 1995. V. 387. №1-2. R. 87 – 94.
5. Potentiometric Flow-Injection Determination of Sugars Using a Metallic Copper Electrode / Alexander P.W. at al. // Analytical Letters. 1985. V. 18. №16. P. 1953 – 1978.
6. Kinetics and Mechanism of Glucose Electrooxidation on Different Electrode-Catalysts / Vasilyev Yu.B. at al. // J. Electroanal. Chem. 1985. V. 196. №1. R. 127 – 144.
7. The Determination of Reducing Carbohydrates Using a Cation-Exchange Column and Potentiometric Detection with a Metallic Copper Electrode / Cowie C.E. at al. // Chromatographia. 1986. V. 21. N7. P. 417 – 419.
8. Electrocatalysis and Detection of Amino Sugars, Alditols, and Acidic Sugars at a Copper-Containing Chemically Modified Electrode / Prabhu S.V. at al. // Anal. Chem. 1989. V. 61. №20. P. 2258 – 2263.
9. Constant Potential Amperometric Detection of Carbohydrates at a Copper-Based Chemically Modified Electrode / Prabhu S.V. at al. // Anal. Chem. 1989. V. 61. №8. P. 852 – 856.
10. Constant Potential Amperometric Detection at a Copper-Based Electrode: Electrode Formation and Operation / Luo P. at al. // Anal. Chem. 1990. V. 62. №7. R. 752 – 755.
11. High-pH ion-exchange separation and electrochemical detection of alditols, carbohydrates and acidic sugars / Prabhu S.V. at al. // Journal of Chromatography A. 1990. V. 503. №1. R. 227 – 235.
12. Comparison of metallic electrodes for constant-potential amperometric detection of carbohydrates, amino acids and related compounds in flow systems / Luo P. at al. // Anal. Chim. Acta. 1991. V. 244. R. 169 – 178.
13. Electrochemical characterization of carbohydrate oxidation at copper electrodes / Marioli J. at al. // Electrochem. Acta. 1992. V. 37. №7. R. 1187 – 1197.
14. Electrocatalytic oxidation of carbohydrates at copper (II) – modified electrodes and its application to flow-through detection / Kano K. at al. // J. Electroanal. Chem. 1994. V. 372. №1-2. R. 137 – 143.