Liquid filtration is an important process in many high-tech and critical manufacturing sectors. Traditional filter materials have a number of limitations. Anodic aluminum oxide stands out due to its unique highly ordered nanoporous structure, high thermal and chemical resistance, and the possibility of surface functionalization. The main areas of successful use of nanoporous aluminum oxide filters are pharmaceuticals and biotechnology, microelectronics, food industry, as well as other specialized environmental and industrial tasks. A comprehensive evaluation of 100 nm alumina liquid filters and comparison with alternative filtration technologies has shown their undeniable advantages in high temperature and aggressive chemical environments. However, significant challeng-es remain, primarily related to cost, contamination, potential fragility, and the need to further improve the long-term stability of some alumina phases or under extremely harsh operating conditions.